Dr. Helen Bassey AKPAN

Dr. Helen Bassey Akpan


Contact: Department of Anatomy, Faculty of Basic Medical Sciences, PAMO University of Medical Sciences

Tel. 08035273712; 2348148989376

Email: hakpan@pums.edu.ng


BSc. Anatomy, University of Calabar

MSc Anatomy, University of Lagos

Ph.D. Anatomy, Olabisi Onabanjo University, Nigeria



Research Interests – Diabetic studies, Neurosciences and Toxicology

My Diabetes studies come with particular interest in unveiling the molecular and structural mechanisms signaling diabetic complications as an attempt to finding the solution to the ravaging menace of diabetes to human health. Here, studies have been carried out using natural extracts from commonly available and affordable medicinal plants as intervention agents in diabetic conditions using animal models. At the neuroscience level, my interest focuses on debilitating conditions occasioned by neuro degenerational diseases whose etiology are more or less difficult to explain but causes identified through macro and micro architectural changes in the nervous tissue. Again, efforts are geared towards contributing the possible ameliorative and by extension the solution to the management of these conditions. Additionally, toxicity has been identified as one of the major underlying factors in disease conditions, so, various researches in my laboratory are ongoing to examine the roles of various toxins in alterations in macro and micro structures of various tissues in the body and by extension identify possible intervention agents to combat the complications arising therefrom.


Positions held, Awards and Honors (Selected)

1. DEO, Department of Anatomy
2. Head, Department of Anatomy
3. Course Co-ordinator and Staff/Level adviser to B.Sc. and Medical students
4. Member, Departmental, NUC accreditation Committee
5. Member, Departmental Disciplinary Committee
6. Coordinator, Departmental Welfare project
7. Staff adviser to Basic Medical Science Student Association (BAMSSA), FBMS, Olabisi Onabanjo University (OOU), Ago-Iwoye, Ogun State, Nigeria.
8. Member, Faculty Board of Studies, FBMS
9. Member of Senate, OOU
10. Member, Postgraduate Examination Board of Examiners, FBMS
11. Member, College Board of Studies, OACHS
12. Member, Faculty Appraisal Committee, FBMS
13. Member, College Appraisal Committee, OACHS
14. Member, Anatomical Society of Nigeria (ASN)
15. Member, Society of Experimental and Clinical Anatomists of Nigeria (SECAN)
16. Member, International Brain Research Organization (IBRO)
17. Member, Neuroscience Society of Nigeria (NSN)
18. Member, Diabetes Association of Nigeria (DAN)
19. Reviewer, (a) Asian Journal of Research in Medical and Pharmaceutical Sciences (b) African Journal of Biochemistry Research
20. Member of Senate, PUMS


Selected Publications

  1. B. Akpan, A. A. Akande, A.O. Ojewale, F. E. Oladipupo, O. F. Akinpelu, S. O. Jimoh (2018) Moringa Oleifera ameliorates nephropathic changes in alloxan-induced diabetic wistar rats. Journal of African Association of Physiological Sciences; 6(2) : 110-118
  2. B. Akpan, O. D. Omotoso, S. A. Adelakun, A. R. Olapade, K. O. Odubela, A. A. Akande, F. E. Oladipupo (2018) Antioxidant Properties of Carica papaya on Cadmium Toxicity on Prefrontal-Cortex of Adult Wistar Rats. European Journal of Medicinal Plants; 23(3): 1-9. ISSN: 2231-0894, NLM ID: 101583475 /EJMP.22753
  3. B. Akpan, O.D. Omotoso, K. O. Odubela, S. A. Adelakun, F. E. Oladipupo, A. A. Akande, and A. R. Olapade (2018) Histo-morphological effects of Carica Papaya on Cadmium Induced Prefrontal-Cortex Damage in Adult Wistar Rats. European Journal of Medicinal Plants. EJMP.16429
  4. B. Akpan, P. D. Shallie, A. K. Adefule, T.K. Adenowo (2017) Lipid Peroxidation is Key to Neuronal Cell Death in the Inferior Colliculus of STZ-Induced Diabetic Rats. Journal of Applied Life Sciences International; 10(1): 1-15
  5. B. Akpan, Omotoso, O. D., Adelakun, S. A., Oladipupo, K.O. Odubela, K. O., A.A. Akande, A. A., Olapade, A.R. (2017) Recuperative Action of Aqueous Carica papaya Extract on Cadmium induced Loss of Nissl Bodies in the Frontal Cortex. Journal of Applied Life Sciences International; 13(4): 1-5, 2017; Article no.JALSI.16430 ISSN: 2394-1103.
  6. D. Shallie, D. J. Talabi, O. O. Olayinka, B. R. Babatunde, H. B. Akpan, O. J. Otulana, O. O. Alese, O. F. Shallie (2017) Flaxseed Oil as a Potential Neuro-protective Agent on the Cerebellum of Rotenone Mice Models of Parkinson’s Diseases. International Journal of Brain and Cognitive Sciences; 6(3): 45 – 50. Doi: 10.593/j.ijbcs.20170603.01


  1. D. Shallie, B. R. Baabtunde, O. O. Olayinka, D. J. Talabi , H. B. Akpan, R. O. Folarin, O. O. Alese, O. F. Shallie (2017) Neurobehavioural and Microstructural Evaluation of the Anti-anxiety Potential of Flaxseed Oil following Rotenone-induced Parkinson’s Disease in Mice. International Neuropsychiatric Disease Journal 9(4): 1 – 12.


  1. D. Shallie, O. O. Olayinka, H. B. Akpan, O. J. Otulana, O. O. Alese, B. R. Baabtunde, D. J. Talabi, O. F. Shallie (2017) Potential Neuro-therapeutic Effect of Flaxseed Oil on the Striatum of Rotenone Mice Model of Parkinson’s Diseases. British Journal of Medicine and Medical Research; 22(1): 1-9


  1. D. Omotoso, J.O. Owolabi, H. B. Akpan, B.J. Dare, E.A. Ashamu, and S. A. Adelakun (2016). Positive Anti-Cadmium Poisoning Anti-Oxidant Effects of Moringa Seed Oil and Cashew Nut Oil in Juvenile Wistar Rats Hippocampus. Journal of Advances in Medical and Pharmaceutical Sciences; 5(1): 1-8.
  2. Shallie, P.D., Adefule, A.K., Akpan, H.B., Olubiyi, O.O., Fakunle, P.B., and Adejomo, E.N. (2010). Lead Toxicity and some subsets of motor skill: Comparative evaluation of adult and prenatally exposed rats. Journal of Neuroscience and Behavioural Health, 2(3): 23-29.
  3. Shallie, P.D., Akpan, H.B., Adefule, A.K. Fakoya, D., Fagbohun, T.R. (2010). Assessment of lithium ingestion on cognition and some subsets of motor skill. J Pharm Bioall Sci, 2:113-7.
  4. Shallie, P.D., Adefule, A.K., Akpan, H.B. Fakoya, D., Adeyomo, E.N. (2010). Analysis of some lipid parameters following lithium administration. African journal of Pharmacy and Pharmacology, 4(5):202-206.